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A Critical Appraisal of Treatments for Bipolar Disorder

Uploader: Fenrirr 3 years ago  
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A 1-year STEP-BD study 26 evaluated the efficacy of medication plus 1 of 3 intensive psychotherapies—cognitive-behavioral therapy, family-focused therapy, and interpersonal and social rhythm therapy—in comparison with medication plus collaborative care, which comprised a brief psychoeducational program in which patients were given a workbook and met with a therapist up to 3 times to be educated about bipolar disorder. Educate patient and family members about use of medication, warning signs of relapse, management of stress, sleep hygiene, eating and exercising regularly, limited caffeine and alcohol intake and management of work and leisure activities. BDNF, which signals through the TrkB receptor to augment cortical development, synaptic plasticity, neurogenesis, and neuronal survival, is known to play a vital role in neuropsychiatric disorders for a review, see Autry and Monteggia, Histone proteins organize DNA into nucleosomes, which are regular repeating structures of chromatin. FXS is the most common inherited single-gene disorder associated with mental retardation.

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